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Public proof of conceptFix available

CVE-2021-25921

A public proof of concept exists; no exploitation attested.

  • Published2021-03-22
  • WeaknessCWE-79

Am I affected?

With a domain, we read the version its public headers and pages expose. A distribution build can carry the fix under an older number.

Description

In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the `Allergies` section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.

Timeline

dates in UTC
  1. 2021-03-2220:15CVE publishedNVD
  2. 2026-10-2319:23EPSS crossed 10 %FIRST EPSS

Observed activity

isMalicious corpus · updated 2026-10-23 18:48 UTC
Indicators tagged with this CVE, per day0 indicators over 7 days
Block these indicators
  • Firewall list (EDL, text): https://api.ismalicious.com/edl/cve/CVE-2021-25921?format=txt
  • CSV export: https://api.ismalicious.com/edl/cve/CVE-2021-25921?format=csv
  • TAXII collection of exploited CVEs
  • The EDL and CSV take an API key on the Pro plan.

Versions per branch

NVD
Open-emr openemr
BranchAffectedFixed in
6.0≥ 2.7.3, ≤ 6.0.0no fix published

as publishedRanges as NVD and OSV publish them; a distribution’s build can be fixed under an older number.

Fix

Advisories and patches

Detection

Nuclei template
none so far
ProjectDiscovery
Exploit-DB
no entry
Exploit-DB
Proof-of-concept repositories
none listed
PoC-in-GitHub

Sources

  • CISA-ADPSSVC decisionpoc2025-04-30
  • OpenCVESSVC decisionpoc—
  • CISA-ADPCVSS 3.15.42025-04-30
  • NVDCVSS 3.15.4read 2026-10-23
  • NVDCVSS 2.03.5read 2026-10-23
  • CISA-ADPweakness (CWE)CWE-792025-04-30
  • NVDweakness (CWE)CWE-79read 2026-10-23
  • FIRST EPSSEPSS score91.1 %read 2026-10-23

Technical details

CVSS v3 Vector
CVSS:3.1/AV:N/AC:L/PR:L/UI:R/S:C/C:L/I:L/A:N
Published
2021-03-22
Last Modified
2026-06-17
NVD status
Modified

Frequently asked questions

What is CVE-2021-25921?

In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the `Allergies` section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.

Is CVE-2021-25921 actively exploited?

A proof-of-concept exploit exists for CVE-2021-25921, but active exploitation has not been confirmed at this time.

What is the CVSS score for CVE-2021-25921?

CVE-2021-25921 has a CVSS v3 base score of 5.4 (MEDIUM severity), with vector string CVSS:3.1/AV:N/AC:L/PR:L/UI:R/S:C/C:L/I:L/A:N.

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